Women Infertility
For women, the older you are, the more likely you are to have problems becoming pregnant and carrying a fetus to term. Fertility rates slowly decline after age 30 and start to plunge after age 35, mostly because the eggs decline in quality. Women are born with all the eggs they'll ever have. So as you age, your eggs age, too. Eggs of older women are more likely to have chromosomal abnormalities, which help account for the higher-than-average miscarriage and Down's syndrome rate among women in their late 30s and 40s. However, donor eggs from younger women make it possible for thousands of older women to give birth.
Aside from poor egg quality, dozens of conditions can cause female infertility. In many cases, the problems can be successfully treated surgically or medically, or bypassed through assisted reproductive techniques.
Here are the most common causes of infertility in women:
* Pelvic inflammatory disease (PID) is an infection of the reproductive tract that usually is caused by a sexually transmitted disease but can also stem from a miscarriage, abortion, childbirth or an intrauterine device (IUD). Among other things, PID can lead to blocked or damaged fallopian tubes.
* Ovulatory dysfunction means that a woman's ovaries are not producing eggs or that egg production has declined because of age, hormonal imbalances or other problems.
* Uterine fibroids can interfere with embryo implantation or fetal growth. At least 40 percent of women have these benign uterine tumors, or myomas.
* Endometriosis is a sometimes painful condition occurring when tissue from the uterine lining occurs abnormally in other areas of the pelvis.
* Diethylstilbestrol (DES), a synthetic estrogen, was given to some women who were at risk for miscarriage during the 1950s and 1960s. Women and men whose mothers took DES while pregnant with them are at high risk for certain reproductive tract cancers and menstrual irregularities. Many DES daughters have an abnormally shaped uterus that can lead to repeated miscarriages. DES sons are prone to cysts in their reproductive tract, undescended testicles and other fertility problems.
* Pelvic adhesions are usually caused by surgery or infection. Pelvic adhesions are actually scar tissue that forms between two or more internal organs. Infertility can occur when the adhesions attach to the ovaries or fallopian tubes.
* Polycystic ovarian disease is a hormonally based condition characterized by scanty or absent menstruation. The disease usually causes multiple cysts to form in the ovaries.
* Immunological infertility is sometimes diagnosed when the woman's immune system produces "anti-sperm antibodies" that attack her partner's sperm. Some men also make antibodies to their own sperm. Immunological infertility can sometimes be treated medically or with assisted reproductive techniques. The theory that immune system abnormalities cause miscarriages is controversial and needs more study.
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